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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5a3bb0d3327766ef3fa20a0d500fd71078a0caf6a7338d5074bd347a0639dc' 
  AND token = 'OlpTSCopYoQSWKgYi/2ASjNxf64KfIq/xrt7cPbyzYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}