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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ee70c9d6eb53371de8c2d041070be687f72c0d7923bbe0d91f0d5f877843e4f' 
  AND token = 'wJOxf2lw+IWWgl4NKgQ7zQeoDl+Io6zA4sVgF2YZXFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}