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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc7bc85e2f031dc05e935d62a9148b0ddc4e962988eab03e97bd80408fc87c0' 
  AND token = 'qROFMAzZzQQhAcDN3eOeRq+FRtxaD2EzjcAc7dmb7kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}