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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273c9fd7404588a037c785ee4bba7b941ac71fb9e3cfad90d67ee83b0850df43' 
  AND token = 'I/szhlq0QOYMD8wV5FF+iDtVlKz2e1rNxpz2aNMf76c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}