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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a76cb302ecab019421e883bb014e0b89c37095fb0a328f34ff40d3eb72475e' 
  AND token = 'b1s+EYM6SRJLNkIAvuZ66a4sgiGUasIV6epqJi+jYy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}