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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c1ccefb27b5e186325dd21bbd001b82feda689ad83bd7cfea02c8446613719' 
  AND token = 'Aol7ldvl9IHhym9Bczz4Y7y40dsbuzx/gh6T/vgB0bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}