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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63575cf8a667075d04577863f8454b1cf6ff8f8ba63877ce1c5e1546b7adb1cc' 
  AND token = 'NFEnJmbXbpHsbN0qDqYZcXQl6diYydfJwwyAuxnFW0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}