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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa35ad49d1c4cd93d921caa4f4cb78f069901a734a321c9b76b02da6eb23335' 
  AND token = 'C54XPs9EpCdxLXMzvFgr4h3GDcOqvXcnwSekA9Jsp2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}