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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b79f6cef2375c2126c1aa204ec46fe776baf213adcf3245b335da633afb9fb' 
  AND token = 'bqAASH21WmrzpQArkPUqR369x/yj/KcmaV495zZSRX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}