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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789dec90a6e811fa5113abdf03dd4659b577e0a0f91d18ba33c2169930dc4b04' 
  AND token = 'Iwfax/rvh2rtpOsGvWaNHUx/VIuTABAFVQTJEcYHyrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}