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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895cf20f8d366a9bb2b777027e8727ac043695068197bfa1aa5d401da5c47a58' 
  AND token = 'JI2l4f2lcYWSfp/YU1fZKy9bGPgJu8P4+L+eDKk24WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}