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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffdcffa99ddc438338a5cd52b1d6072dd47258bb8d01fc53ba99574eaf04c0dc' 
  AND token = 'UY4Z5YXszPjCu2v79Jr8wkPBIBPILl9kje0pP6vSa8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}