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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8420cf0ff143fcf518d533897872059487479451e62f7a5babcf326d05f9279' 
  AND token = 'ddUTMMqHuDk7bEzUxqNDyToPE8mVE5iVu6fe+/wlxfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}