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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f014595dc200f8f8bab685020ba013262cada73852a438b87e5bec4e0c2be227' 
  AND token = 's+3T9uJe1NQMT/XuQnOp5n8vYUAEs36/LH/eQqj6DFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}