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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65ed7ba1a4482fa1312f011083a492b4abe0455a484c1f82a2a463598c0644ad' 
  AND token = 'vT/+Q7XuFwpK79FqRjk9PXtaI8u1cy88FKckly7mMjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}