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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03ea934d662cd60afa367778f1318a1e1480295795725dd0970144dfbc6b37a4' 
  AND token = 'vUfMUCvHsbjZBICq53r5rGE0IIydN9yWBPs6SU/EmOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}