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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578f80851177a86278ee823a9f1d9f55e63a198d5617faafba2ca414bbd1135a' 
  AND token = 'c7Tz83Ii67yaT28Gz31kIsiXt4pHhehB7xIMGmOFA7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}