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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e6dfee185f2997d23a0d4c95be15c3acaaeb3915f63f55f21935d12112390d' 
  AND token = 'fL2edHCiVju3iQnBH+Bg/jlJYky9tx+w5X+aymkIrdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}