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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff73749fd5f16962c787b94a4d7e45b31abd3e4fea6718540a4ac7e41932590' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}