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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18c327da2071852e75e6bb1c1c582e96fac3ff8f97c308d868e03ad475b5f93' 
  AND token = 'gOMroUy4CiwaA3aDLqH7VzK4i4tOWsD2yKUIJJA5ZAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}