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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002bd0e38dd6f6849b62e792c25c88a6dbee233dc9eb3d26c23b2736c18d471c' 
  AND token = 'HODRWanwqGoYxQcMcJSjLed/iHf6fOOunMsSft2/g28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}