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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed3a4a7f630f9d337adb17ac26da13ee30b4cabe09abb41005dac9edcf7f7652' 
  AND token = 'JIN/oeGyOz0pgoK25LMAA1BFC2U04MF6JXJ/F63MXBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}