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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fdb3e82f0cc670faf043b7b9d16c814a1fd22eb4176aba39ff2596dae3c95e6' 
  AND token = 'Gy+b3RNSbWXIpjdk/vt5Y3cgcqvrUpNmUctRQjA9Ims=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}