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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050b61ad4d59f9235fa9f4938806f62eff39066b71f2c40e7c96ea5eceb7042f' 
  AND token = '41oRbGXuhW277fJtU+Je/rpNnME27SIo8mthM36mQcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}