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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c88257cc24740f8cdd1b6ff8160c6f7684428b3bfe05b9a7cee19ffd824631d5' 
  AND token = '8awQ0+fOQ3cfwxMGefXB3YBY8bJgAqxZT3RqmY51xt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}