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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b16be59b3b299e1e3e9a5ee3b6578592f7564df4d0f5414f83c3e7ee0c0b5b' 
  AND token = 'mpVHa9zb1/SEo3bQTFI7w3QEyO0lNq611Uh0m2O9Mg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}