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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018519c3543aea28b275fdd6550070a168fbfd37fd7f7c3e29e0bbdefaa93f89' 
  AND token = 'RUgLtORd/k04mxOxWfu6v1nsMZwXkL2u4MqVOBxt2hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}