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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74cdeb4a54082637fd31dddeeda54cda9d72daf50480fa8a96b7a1985a75ba2a' 
  AND token = 'V+hwmBEJwlHXOA9F9RGuRrBbWaPyFLmkI7rzTZstiVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}