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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433e373afe57c9ef1cc1e38bffc3b78ffb8f8a58ce5a4677873e96f3d6b45277' 
  AND token = 'slmHHJYeAACRwiBdEzsFwX/giB/rsoQRF0rV1wXDzx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}