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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c82cd4b0e04b93888c63ce9fbff3a2192e69d6e3bdd2c5e575aa73bbdb909b8' 
  AND token = 'leLoFJR+WFJUtSjhrLICnbtSnCDC0SfA5STaaATtcdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}