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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abdf38dd283081fa7c449a96d48ee3451c0c34044909f9d3c655d682b03f4dc0' 
  AND token = 'bdK7BC//xwmeEt3UQH6JOcGcpUjSzE5zvrvbGdb+1JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}