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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1354da256195c0e09ac7960bc6a178d72b018e901864d778af3b4a587d721ec' 
  AND token = '6o6jqrvfQ8jn/7HdYYStEKpjyOB8qADL5Kt3bDmKQz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}