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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3257730e43e27889c25961b3b89b8807fdd7cdcfcea8371f4822f2a4afe969eb' 
  AND token = 'rfHSWXz2h2is4SEQos5oDARkRBDK+sg37kaBjzH0UM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}