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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df42fbf2ad2557560c691de271a137a358a3b261d68a9caa86fe935c20fef0ba' 
  AND token = 'TYSsNkMIjImmxcPn2/9j9lmehesfemNk9LQo/7yJ9fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}