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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c35e29cdd1f6b4aa5b9ce42021fcce46e635a8588e87d70964bf5a35c9ae93' 
  AND token = 'mB/5uO0vXBoHKokd6Xn8LTE62oqZ99XBez+tyIYdTfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}