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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45f22656086d726f0c27c1c9deba9bb89a522806efa2d4c087092c23485d0c0' 
  AND token = 'x8yNowsWMOERtsntOOA/qldPfvq3PXjAqfQ3JHpWp4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}