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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb57b29a2ffdbfe548eebb156fc6e81e6c35de88d655e8675709cc75be90fca' 
  AND token = 'eNkB02tW+5CZvKleiVh+7ox6FhAVqejKLr2bd28ZuPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}