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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e1ec9f2c347225310a30e6f2f058be18132bac9c4ed2560561b02b9e48d8ad' 
  AND token = 'IPcuZoGYBv7YTzfeg80uCOgi0mAv3ClfT+eVJe4+Zrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}