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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e68a62df1b1b8509415ac7343d7c0b6d51ea76b5e36cfe5f75746370ccc10d' 
  AND token = 'sVuLvI60c7Gn8ud/2cTaUnt22GEkeupdtWa/XZHSHHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}