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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6d952970c8eaf9dce4e5aa32bad623140bab5684436b8e3744996574b15805' 
  AND token = '+0jnU5APN9U+CREIB41igJ7dLeMAfgDBuSct/8k9pRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}