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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4777ea4c8dc28f071a8a6270936a86783cf8cf4145eff4f405e08e7db6e95888' 
  AND token = 'vVrbasdWCnCJB7QHWZqna6E1hCsDzvAcXiQvTg3wASs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}