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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c155476a0046edb5152b456a697307c1275881b26f2b7f82b10654c834030716' 
  AND token = 'trFwS6EiMJWS97Kd7KLEUkeeWM/uLHXsOyo0tzMVrQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}