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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a129090d97664217c60c0e949e34e6938b94cd6566210fea7b21f33d35efc71' 
  AND token = 'HG/obZanv5zler9kVx05PobgDBUbfdL7p0KrqCsBLkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}