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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a70ad2048e9a1fcb97aebaac050767264dc919385a74174a567b2bb6d411ff8' 
  AND token = 'PeSfrDGOVNzkpJu0M876qrTnqckP1BL7LOFo9QnWrqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}