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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c00cd9b80aa6c9ed6c3aeb6155b1e0f7045420e1b16b6d48d7622ae283a29add' 
  AND token = 'wGT0N8UptYE2mNZPLx6iyouSPb6ecFfATgPSwPZY8d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}