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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '101b2c83a914540de798e6cb6d44eb7ede6b0058a5513e9c9ab3b52a4fbab262' 
  AND token = 'PsPdRlG8OQHgSk8SExsY+VQm2lW50DwGTlfrSH2Z7gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}