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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adc0f835fa8b5b41d65d0428cad73c0fcd99f731ef87aa7962072022252f21f2' 
  AND token = 'dLrbjsWC6b7LwaAzcIt7svP0LxAdKGDfkLsMAheuzfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}