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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'feba63688a3846a8384324ad2c49a0039161574a3acf0f19b210ac2627d3a564' 
  AND token = '109nrzZ+jOfDl0TNCPPB547tNCivE9cTld04nE/Vd6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}