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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca7cef2a63a771ff08f394d0c54e44c69e0e05deb3e34aa6ed23f153e8db79f' 
  AND token = 'LOonlGVrTk6uP8q3xAmOjnRWrWe5FG1BkSzy1FSgjY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}