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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b498c93264bea4fa045b94b242a13c78a5d823329d836d35e2519aa923ba1c' 
  AND token = '4MnJhkn5ew/XDXQYOxNStxG4HjwyK2xV2gxW8kabxfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}